Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

被引：12

作者：

Brown, R ^{[1
]}

Smith, WE ^{[1
]}

Graham, D ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 07期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(02)02886-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1339 / 1342

页数：4

共 17 条

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