On the use of the word 'epigenetic'

被引:257
作者
Ptashne, Mark [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, New York, NY 10021 USA
关键词
D O I
10.1016/j.cub.2007.02.030
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Over the past few years we have seen an odd change, or extension, in the use of the word 'epigenetic' when describing matters of gene regulation in eukaryotes. Although it may generally tie that it is not worth arguing over definitions, this is true only insofar as the participants in the discussion know what each other means. I believe the altered use of the term carries baggage from the standard definition that can have misleading implications. Here I wish to probe our use of language in this way, and to show how such a discussion leads to some more general considerations concerning gene regulation.
引用
收藏
页码:R233 / R236
页数:4
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