Preparation of nanofibers containing the microalga Spirulina (Arthrospira)

被引：63

作者：

de Morais, Michele Greque ^{[2
]}

Stillings, Christopher ^{[1
]}

Dersch, Roland ^{[1
]}

Rudisile, Markus ^{[1
]}

Pranke, Patricia ^{[3
]}

Vieira Costa, Jorge Alberto ^{[2
]}

Wendorff, Joachim ^{[1
]}

机构：

[1] Univ Marburg, Dept Chem, D-35032 Marburg, Germany

[2] Fed Univ Rio Grande, Sch Chem & Food, Biochem Engn Lab, BR-96201900 Rio Grande, RS, Brazil

[3] Univ Fed Rio Grande do Sul, Fac Pharm, Hematol & Stem Cell Lab, BR-90610000 Porto Alegre, RS, Brazil

来源：

BIORESOURCE TECHNOLOGY | 2010年 / 101卷 / 08期

关键词：

Electrospinning; Microalgae; Nanofibers; Polymer; Spirulina;

D O I：

10.1016/j.biortech.2009.11.059

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

Spirulina is a microalga which offers biological functions highly favorable for tissue engineering. Highly porous scaffolds can be produced by electrospinning containing biomass of Spirulina. The goal of this contribution was therefore to establish spinning conditions allowing to produce well defined nanofibers with diameters down to about 100 nm and to produce nanofibers with various concentration of the biomass for subsequent studies in tissue engineering applications. The experimental results reveal that the blend system PEO/biomass is behaved surprisingly well in electrospinning. Very thin bead-free nanofibers with diameters of about 110 nm can be produced for different biomass contents of up to 67 wt.% of the nanofibers and for PEO concentrations in the spinning solution well below 4 wt.%. These results suggest to us the use of the biomass containing nanofibers as extracellular matrices for stem cell culture and future treatment of spinal chord injury. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2872 / 2876

页数：5

共 10 条

[1] MICROALGAE AS SOURCES OF PHARMACEUTICALS AND OTHER BIOLOGICALLY-ACTIVE COMPOUNDS [J].

BOROWITZKA, MA .

JOURNAL OF APPLIED PHYCOLOGY, 1995, 7 (01) :3-15

[2] Improving Spirulina platensis biomass yield using a fed-batch process [J].

Costa, JAV ;

Colla, LM ;

Duarte, PF .

BIORESOURCE TECHNOLOGY, 2004, 92 (03) :237-241

[3]

Henrikson R., 1994, Microalga Spirulina - Superalimento del futuro

[4] Activation of the human innate immune system by Spirulina:: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis [J].

Hirahashi, T ;

Matsumoto, M ;

Hazeki, K ;

Saeki, Y ;

Ui, M ;

Seya, T .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2002, 2 (04) :423-434

[5] Relationship between physicochemical variables and productivity in open ponds for the production of Spirulina:: a predictive model of algal yield [J].

Jiménez, C ;

Cossío, BR ;

Niell, FX .

AQUACULTURE, 2003, 221 (1-4) :331-345

[6] Electrospinning of sodium alginate with poly(ethylene oxide) [J].

Lu, Jian-Wei ;

Zhu, Yong-Liang ;

Guo, Zhao-Xia ;

Hu, Ping ;

Yu, Jian .

POLYMER, 2006, 47 (23) :8026-8031

[7] Sulfated polysaccharides from red microalgae have antiinflammatory properties in vitro and in vivo [J].

Matsui, MS ;

Muizzuddin, N ;

Arad, S ;

Marenus, K .

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2003, 104 (01) :13-22

[8] Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis [J].

Mishima, T ;

Murata, J ;

Toyoshima, M ;

Fujii, H ;

Nakajima, M ;

Hayashi, T ;

Kato, T ;

Saiki, I .

CLINICAL & EXPERIMENTAL METASTASIS, 1998, 16 (06) :541-550

[9]

Rufino M, 2007, COMUNICADO TECNICO O, V128, P1

[10]

Safi S, 2007, J APPL POLYM SCI, V104, P3245, DOI 10.1002/app.25696

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