Clinical research for older adults in rural areas: the MINDED study experience

被引:9
作者
Fougere, Bertrand [1 ,5 ]
Aubertin-Leheudre, Mylene [2 ,3 ]
Vellas, Bruno [1 ,4 ,5 ]
Andrieu, Sandrine [4 ]
Demougeot, Laurent [1 ]
Cluzan, Celine [1 ]
Cesari, Matteo [1 ,4 ,5 ]
机构
[1] Ctr Hosp Univ Toulouse, Gerontopole, Toulouse, France
[2] Univ Quebec A Montreal, Dept Kinanthropol, Montreal, PQ, Canada
[3] Inst Univ Geriatrie Montreal, Ctr Rech, Montreal, PQ, Canada
[4] Univ Toulouse III Paul Sabatier, INSERM, UMR1027, Toulouse, France
[5] Univ Toulouse III Paul Sabatier, Inst Vieillissement, Gerontopole, 37 Allees Jules Guesde, F-31000 Toulouse, France
关键词
Older adult; Rural areas; Randomized controlled trial; MINDED; DISABILITY; TRIALS;
D O I
10.1007/s11357-016-9892-3
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Due to the growing need to make clinical decisions based on valid and objective scientific evidence, the number of randomized controlled trials (RCTs) has increased over the last three decades. Nevertheless, evidence-based medicine has still limited applicability in older adults, because they are often excluded from clinical trials. Evidence-based medicine is even more challenging in rural areas, as its remote environment provides additional barriers. Nevertheless, given the high prevalence of older adults living in rural settings, research in this type of environment has become crucial. This can only be accomplished by considering the multiple additional challenges of these regions. In this paper, we examine potential environmental, procedural, and participants' barriers to the management of a RCT in a rural area. Possible solutions and suggestions are provided based on our experience-from the Multidomain Intervention to preveNt Disability in ElDers (MINDED) project.
引用
收藏
页码:1 / 4
页数:4
相关论文
共 13 条
[1]
Barriers to the participation of African-American patients with cancer in clinical trials - A pilot study [J].
Advani, AS ;
Atkeson, B ;
Brown, CL ;
Peterson, BL ;
Fish, L ;
Johnson, JL ;
Gockerman, JP ;
Gautier, M .
CANCER, 2003, 97 (06) :1499-1506
[2]
[Anonymous], 2011, GLOB HLTH AG
[3]
A Self-Reported Screening Tool for Detecting Community-Dwelling Older Persons with Frailty Syndrome in the Absence of Mobility Disability: The FiND Questionnaire [J].
Cesari, Matteo ;
Demougeot, Laurent ;
Boccalon, Henri ;
Guyonnet, Sophie ;
Van Kan, Gabor Abellan ;
Vellas, Bruno ;
Andrieu, Sandrine .
PLOS ONE, 2014, 9 (07)
[4]
The Multidomain Intervention to preveNt Disability in ElDers (MINDED) project: Rationale and study design of a pilot study [J].
Cesari, Matteo ;
Demougeot, Laurent ;
Boccalon, Henri ;
Guyonnet, Sophie ;
Vellas, Bruno ;
Andrieu, Sandrine .
CONTEMPORARY CLINICAL TRIALS, 2014, 38 (01) :145-154
[5]
Clinical research by community oncologists [J].
Cohen, GI .
CA-A CANCER JOURNAL FOR CLINICIANS, 2003, 53 (02) :73-81
[6]
Cutler S J, 1988, J Rural Health, V4, P11, DOI 10.1111/j.1748-0361.1988.tb00175.x
[7]
Functional disability and health care expenditures for older persons [J].
Fried, TR ;
Bradley, EH ;
Williams, CS ;
Tinetti, ME .
ARCHIVES OF INTERNAL MEDICINE, 2001, 161 (21) :2602-2607
[8]
Matteo Cesari LD, 2012, J FRAILTY AMP AGING, V1, P169
[9]
Maurer LH, 2001, J CANCER EDUC, V16, P89
[10]
Rogers C, 2002, RURALAM, P31