Clinical pharmacology of antifungal compounds

被引:93
作者
Groll, AH
Gea-Banacloche, JC
Glasmacher, A
Just-Nuebling, G
Maschmeyer, G
Walsh, TJ
机构
[1] Univ Munster, Med Ctr, Ctr Bone Marrow Transplantat, Infect Dis Res Program, D-48149 Munster, Germany
[2] Univ Munster, Med Ctr, Dept Pediat Hematol Oncol, D-48149 Munster, Germany
[3] NCI, Expt Transplantat & Immunol Branch, NIH, Bethesda, MD 20892 USA
[4] Univ Bonn, Dept Internal Med 1, D-53121 Bonn, Germany
[5] Goethe Univ Frankfurt, Dept Internal Med, Div Infect Dis, D-60590 Frankfurt, Germany
[6] Univ Hosp Berlin, Charite, Dept Internal Med, Div Hematol & Oncol, D-13353 Berlin, Germany
[7] NCI, Pediat Oncol Branch, Immunocompromised Host Sect, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S0891-5520(02)00068-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Prompted by the worldwide surge in fungal infections, the past decade has witnessed a considerable expansion in antifungal drug research. New compounds have entered the clinical arena, and major progress has been made in defining paradigms of antifungal therapies. This article provides an up-to-date review on the clinical pharmacology, indications, and dosage recommendations of approved and currently investigational therapeutics for treatment of invasive fungal infections in adult and pediatric patients.
引用
收藏
页码:159 / +
页数:34
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