High-throughput experimentation in pharmaceutical process R&D: Developing a new software workflow to overcome downstream data-analysis bottlenecks and improve productivity

被引：13

作者：

Higginson, PD ^{[1
]}

Sach, NW ^{[1
]}

机构：

[1] Pfizer Ltd, Pfizer Global Res & Dev, Sandwich CT13 9NJ, Kent, England

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2004年 / 8卷 / 06期

关键词：

D O I：

10.1021/op049873u

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new software workflow is described to overcome our data analysis, data-modification, and visualisation bottlenecks. Through a combination of in-house and external supplier expertise, a software workflow has been developed to tackle the mass of data generated from high-throughput experimentation. Also described is our solution to high-throughput HPLC reaction analysis. In overcoming these bottlenecks, the productivity of our screening technology has dramatically increased.

引用

页码：1009 / 1014

页数：6