Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo

被引:133
作者
Dzierzak, E
Medvinsky, A
de Bruijn, M
机构
[1] Erasmus Univ, Fac Med, Dept Cell Biol & Genet, NL-3000 DR Rotterdam, Netherlands
[2] Univ Edinburgh, Ctr Genome Res, Edinburgh EH9 3JQ, Midlothian, Scotland
来源
IMMUNOLOGY TODAY | 1998年 / 19卷 / 05期
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/S0167-5699(98)01258-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A considerable amount of data has been accumulated on the developmental origins of the mammalian haematopoietic system, particularly within the intraembryonic aorta-gonad-mesonephros (AGM) region. Here, Elaine Dzierzak, Alexander Medvinsky and Marella de Bruijn review cellular and molecular data on mouse developmental haematopoiesis and discuss the implications for the long-held notion of the yolk sac origin of the adult haematopoietic system.
引用
收藏
页码:228 / 236
页数:9
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