Gabapentin in late-onset poststroke seizures

被引：68

作者：

Alvarez-Sabín, J

Montaner, J

Padró, L

Molina, CA

Rovira, R

Codina, A

Quintana, R

机构：

[1] Hosp Gen Valle Hebron, Serv Neurol, Unidad Cerebrovasc, Barcelona, Spain

[2] Hosp Gen Valle Hebron, Dept Neurol, Epilepsy Unit, Barcelona, Spain

来源：

NEUROLOGY | 2002年 / 59卷 / 12期

关键词：

D O I：

10.1212/01.WNL.0000038388.57824.B6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation. or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.

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页码：1991 / 1993

页数：3

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