Preserved postoperative penile size correlates well with maintained erectile function after bilateral nerve-sparing radical retropubic prostatectomy

被引:51
作者
Briganti, Alberto
Fabbri, Fabio
Salonia, Andrea
Gallina, Andrea
Felix, K.-H. Chun
Deho, Federico
Zanni, Giuseppe
Suardi, Nazareno
Karakiewicz, Pierre I.
Rigatti, Patrizio
Montorsi, Francesco
机构
[1] Univ Vita Salute San Raffaele, Hosp San Raffaele, Dept Urol, I-20132 Milan, Italy
[2] Univ Hamburg, Dept Urol, Hamburg, Germany
[3] Univ Montreal, Canc Prognost & Hlth Outcomes Unit, Montreal, PQ, Canada
关键词
erectile dysfunction; penile size; radical prostatectomy;
D O I
10.1016/j.eururo.2007.03.050
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Objectives: Controversial data on penile length after radical retropubic prostatectomy are available. We hypothesised that postoperative penile size correlates to erectile function following bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). Methods: Thirty-three consecutive patients with a preoperative erectile function domain of the International Index of Erectile Function (IIEF-EF) score indicating full potency (>= 26) were prospectively enrolled. All patients underwent BNSRRP performed by one high-volume surgeon. All patients were preoperatively evaluated by IIEF-EF, analysis of comorbidities, physical examination, and penile power colour Doppler ultrasound using intracavernosal injection of prostaglandin El (PGE(1)) 20 [mu g plus audiovisual and manual genital stimulation. Penile length and circumference were measured in flaccidity and at maximum erection. Six months postoperative, patients were assessed with the same protocol plus general assessment questions investigating penile structure and function. Statistical analysis was performed with an independent sample t test. Results: Mean patient age was 56.5 yr. We found no difference between the preoperative and the 6-mo postoperative mean IIEF-EF domain score (27.2 vs, 26.7, respectively; p = 0.35). No difference was found in penile colour Doppler evaluation between the preoperative and postoperative periods (all p values >= 0.3). We found no differences in penile length and circumference between the preoperative and postoperative evaluation either in the flaccid or in the erect state. Mean flaccid penile length (cm; preop vs. postop): 13.2 vs. 13 (p = 0.6). Mean flaccid penile circumference (cm; preop vs. postop): 11.1 vs. 11 (p = 0.7). Mean erect penile length (cm; preop vs. postop): 16.8 vs. 16.5 (p = 0.08). Mean erect penile circumference (cm; preop vs. postop): 15.6 vs. 15.3 (p = 0.2). Conclusions: This is the first report on penile changes in flaccidity and at maximum erection after BNSRRP in patients treated by one high-volume Surgeon. The postoperative preservation of erectile function positively correlated with the maintenance of penile length following surgery. We found no change in penile size after surgery. (c) 2007 European Association of Urology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:702 / 707
页数:6
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