Uncatalyzed conversion of linear α-nitro ketones into amides by reaction with primary amines under solventless conditions

被引：29

作者：

Ballini, R ^{[1
]}

Bosica, G ^{[1
]}

Fiorini, D ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, MC, Italy

来源：

TETRAHEDRON | 2003年 / 59卷 / 08期

关键词：

nitro ketones; amides; carbon-carbon bond; cleavage; solventless;

D O I：

10.1016/S0040-4020(03)00022-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of linear alpha-nitro ketones with primary amines allows the formation of amides through the cleavage of the carbon-carbon bond between the carbonyl group and the carbon-nitro group moiety, promoted by the nucleophilic effect of the amine. The reaction is performed at room temperature, without any catalyst and/or solvent. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：1143 / 1145

页数：3

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