Metastatic cancer involving pancreatic duct epithelium and its mimicry of primary pancreatic cancer

被引：14

作者：

Matsukuma, S ^{[1
]}

Suda, K ^{[1
]}

Abe, H ^{[1
]}

Ogata, S ^{[1
]}

Wada, R ^{[1
]}

机构：

[1] JUNTENDO UNIV,SCH MED,DEPT PATHOL 1,TOKYO 113,JAPAN

来源：

HISTOPATHOLOGY | 1997年 / 30卷 / 03期

关键词：

pancreas; metastasis; pancreatic duct; in situ carcinoma;

D O I：

10.1046/j.1365-2559.1997.d01-604.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We investigated 47 autopsy cases of metastatic cancer involving the pancreas. Metastatic disease in nine cases involved the pancreatic duct epithelium. In two cases, metastatic cancer cells showed Pagetoid features, In three cases, pancreatic metastatic disease showed solitary proliferation with focal in situ carcinoma-like lesions mimicking primary pancreatic cancers, Each of these three cases had primary lung adenocarcinomas. Serial sections revealed abrupt borders between the in situ carcinoma-like lesions and the non-cancerous epithelium. Primary pancreatic cancers did not show Pagetoid features or abrupt borders between the cancerous and non-cancerous epithelium. We conclude that the possible diagnosis of pancreatic metastasis should be carefully ruled out in the histological detection of latent primary pancreatic cancer.

引用

页码：208 / 213

页数：6

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