PtCl2-catalyzed transannular cycloisomerization of 1,5-enynes:: A new efficient regio- and stereocontrolled access to tricyclic derivatives

被引:67
作者
Blaszykowski, C [1 ]
Harrak, Y [1 ]
Gonçalves, MH [1 ]
Cloarec, JM [1 ]
Dhimane, AL [1 ]
Fensterbank, L [1 ]
Malacria, M [1 ]
机构
[1] Univ Paris 06, CNRS, UMR 7611, Chim Organ Lab, F-75252 Paris 05, France
关键词
D O I
10.1021/ol048463n
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
(GRAPHICS) Transannular PtCL2-catalyzed cycloisomerizations open a new route to cyclopropanic tricyclic systems. Ketones A or C were efficiently prepared from the same cycloundec-5-en-1-yne precursor B, depending on the substituent at the propargylic position (either benzoate or methoxy).
引用
收藏
页码:3771 / 3774
页数:4
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