Assessment of infant brain development with frequency-domain near-infrared spectroscopy

被引：135

作者：

Franceschini, Maria Angela

Thaker, Sonal

Themelis, George

Krishnamoorthy, Kalpathy K.

Bortfeld, Heather

Diamond, Solomon G.

Boas, David A.

Arvin, Kara

Grant, P. Ellen

机构：

[1] Massachusetts Gen Hosp, Athinuola A Martinos Ctr, Charlestown, MA 02129 USA

[2] Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Dept Neonatol, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Div Pediat Neurol, Boston, MA 02114 USA

[5] Texas A&M Univ, Dept Psychol, College Stn, TX 77843 USA

来源：

PEDIATRIC RESEARCH | 2007年 / 61卷 / 05期

关键词：

D O I：

10.1203/pdr.0b013e318045be99

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This is the first report to demonstrate quantitative monitoring of infant brain development with frequency-domain near-infrared spectroscopy (FD-NIRS). Regionally specific increases in blood volume and oxygen consumption were measured in healthy infants during their first year. The results agree with prior PET and SPECT reports; but, unlike these methods, FD-NIRS is portable and uses nonionizing radiation. Further, new information includes the relatively constant tissue oxygenation with age and location, suggesting a tight control between local oxygen delivery and consumption in healthy infants during brain development. FD-NIRS could become the preferred clinical tool for quantitatively assessing infant brain development.

引用

页码：546 / 551

页数：6

共 36 条

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