Effective transformation of aldoximes to nitriles by dehydration with 2-methylene-1,3-dioxepane in the presence of a Lewis acid catalyst

被引：21

作者：

Fukuzawa, S

Yamaishi, Y

Furuya, H

Terao, K

Iwasaki, F

机构：

[1] WACKER CHEM E ASIA LTD,SHINJUKU KU,TOKYO 169,JAPAN

[2] TOKUYAMA RES LAB,TOKUYAMA,YAMAGUCHI 745,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(97)01715-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The dehydration of aldoximes with 2-methylene-1,3-dioxepane (MDO) proceeds smoothly in the presence of a catalytic amount of Lewis acid such as scandium(III) triflate to give corresponding nitriles in moderate to high yields under mild conditions. (C) 1997 Elsevier Science Ltd.

引用

页码：7203 / 7206

页数：4