Innate versus adaptive immunity: A paradigm past its prime?

被引：40

作者：

Borghesi, Lisa ^{[1
]}

Milcarek, Christine ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Immunol, Dept Sch Med, Pittsburgh, PA 15261 USA

来源：

CANCER RESEARCH | 2007年 / 67卷 / 09期

关键词：

D O I：

10.1158/0008-5472.CAN-07-0182

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Studies in tumor immunology have relied upon the classic paradigm of distinct innate and adaptive parts of the immune system. However, recent advances in immunology suggest that this division may be overly simplistic, with emerging evidence of a breakdown in conventional hallmarks of each system. Here, we provide an overview of this area and discuss how the concept of a continuum of immune cell populations suggests novel areas of investigation in cancer research.

引用

页码：3989 / 3993

页数：5

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