Intravenous valproate is well tolerated in unstable patients with status epilepticus

被引：112

作者：

Sinha, S

Naritoku, DK

机构：

[1] So Illinois Univ, Dept Neurol, Springfield, IL 62794 USA

[2] So Illinois Univ, Dept Pharmacol, Springfield, IL 62794 USA

来源：

NEUROLOGY | 2000年 / 55卷 / 05期

关键词：

D O I：

10.1212/WNL.55.5.722

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors reviewed hospital records of 13 patients with status epilepticus and hypotension who received TV valproate therapy. Most patients were elderly (74.4 +/- 12.5 [SD] years) and received a loading dose of valproate of 25.1 +/- 5.0 mg/kg (range 14.7 to 32.7), at a rate of 36.6 +/- 25.1 mg/min (range 6.3 to 100). There were no significant changes in blood pressure, pulse, or use of vasopressors. The data suggest that valproate loading is well tolerated, even in patients with cardiovascular instability.

引用

页码：722 / 724

页数：3

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