Effects of various resin composite (co)monomers and extracts on two caries-associated micro-organisms in vitro

被引:207
作者
Hansel, C
Leyhausen, G
Mai, UEM
Geurtsen, W [1 ]
机构
[1] Med Univ Hannover, Dept Conservat Dent & Periodontol, D-30623 Hannover, Germany
[2] Med Univ Hannover, Inst Med Microbiol, D-30623 Hannover, Germany
关键词
dental composites; residual monomers; Streptococcus sobrinus; Lactobacillus acidophilus; microbial effects;
D O I
10.1177/00220345980770010601
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. The purpose of this study was to examine the effects of important resin composite (co)monomers (Bis-GMA, UDMA, TEGDMA, EGDMA) and extracts of two commercial dental composites with similar composition (composite A, Arabesk(TM); composite S, Superlux(TM)) on the growth of the two cariogenic bacterial pathogens Streptococcus sobrinus and Lactobacillus acidophilus.? It was found that neither the monomers Bis-GMA and UDMA, nor the comonomer EGDMA, nor the extract of composite A influenced the growth of S, sobrinus in the log phase. The comonomer TEGDMA and the extract of composite S were found to stimulate growth in the log phase, but this stimulation was not statistically significant. However, EGDMA, TEGDMA, and the extract of composite S did stimulate the total growth of S. sobrinus. In the assays with L., acidophilus, Bis-GMA, UDMA, and the extract of composite A inhibited the growth in the log phase, whereas TEGDMA stimulated it. Furthermore, EGDMA, TEGDMA, and the extract of composite S stimulated the biomass production of L., acidophilus. We conclude from our results that a release of EGDMA and TEGDMA from resin composites should be avoided due to their growth-stimulating effects on the caries-associated micro-organisms S. sobrinus and L. acidophilus.
引用
收藏
页码:60 / 67
页数:8
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