Zwitterionic polymerization of lactide to cyclic poly(lactide) by using N-heterocyclic carbene organocatalysts

被引：325

作者：

Culkin, Darcy A.

Jeong, Wonhee

Csihony, Szilard

Gomez, Enrique D.

Balsara, Nitash R.

Hedrick, James L.

Waymouth, Robert M. ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

[2] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

[3] IBM Corp, Almaden Res Ctr, San Jose, CA 95120 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 15期

关键词：

cyclization; lacticles; N-heterocyclic carbenes; ring-opening polymerization; zwitterionic polymerization;

D O I：

10.1002/anie.200604740

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Closing the loop: The zwitterionic ring-opening polymerization of lactide in the presence of N-heterocyclic carbenes generates well-defined cyclic poly(lactide) (see scheme). The polymerization is rapid and produces macrocyclic polymers with high purity and exceptional control of molecular weight and polydispersity. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2627 / 2630

页数：4

共 30 条

[1] ELECTRONIC STABILIZATION OF NUCLEOPHILIC CARBENES [J].