Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size

被引：125

作者：

Allamaneni, SSR

Naughton, CK

Sharma, RK

Thomas, AJ

Agarwal, A

机构：

[1] Cleveland Clin Fdn, Ctr Adv Res Human Reprod Infertil & Sexual Funct, Glickman Urol Inst, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Dept Obstet & Gynecol, Cleveland, OH 44195 USA

[3] Washington Univ, Sch Med, Div Urol Surg, St Louis, MO 63110 USA

来源：

FERTILITY AND STERILITY | 2004年 / 82卷 / 06期

关键词：

D O I：

10.1016/j.fertnstert.2004.04.071

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Increased levels of reactive oxygen species (ROS) are associated with clinical varicoceles; however, its correlation with varicocele grade and testis size is unknown. In our study, seminal ROS levels showed significant correlation with left varicocele grade and significantly elevated seminal ROS levels were seen in men with left varicocele grade 2 and 3 compared to grade 1. (C)2004 by American Society for Reproductive Medicine.

引用

页码：1684 / 1686

页数：3

共 19 条

[1] Role of oxidants in male infertility: rationale, significance, and treatment
Agarwal, A
Saleh, RA
[J]. UROLOGIC CLINICS OF NORTH AMERICA, 2002, 29 (04) : 817 - +
[2] Role of sperm chromatin abnormalities and DNA damage in male infertility
Agarwal, A
Said, TM
[J]. HUMAN REPRODUCTION UPDATE, 2003, 9 (04) : 331 - 345
[3] ALVAREZ JG, 1987, J ANDROL, V8, P338
[4] Varicocelectomy improves intrauterine insemination success rates in men with varicocele
Daitch, JA
Bedaiwy, MA
Pasqualotto, EB
Hendin, BN
Hallak, J
Falcone, T
Thomas, AJ
Nelson, DR
Agarwal, A
[J]. JOURNAL OF UROLOGY, 2001, 165 (05) : 1510 - 1513
[5] EXPERIENCE WITH 425 SUB-FERTILE MALE PATIENTS
GREENBERG, SH
LIPSHULTZ, LI
WEIN, AJ
[J]. JOURNAL OF UROLOGY, 1978, 119 (04) : 507 - 510
[6] Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity
Hendin, BN
Kolettis, PN
Sharma, RK
Thomas, AJ
Agarwal, A
[J]. JOURNAL OF UROLOGY, 1999, 161 (06) : 1831 - 1834
[7] The role of reactive oxygen species in testicular dysfunction associated with varicocele
Köksal, IT
Tefekli, A
Usta, M
Erol, H
Abbasoglu, S
Kadioglu, A
[J]. BJU INTERNATIONAL, 2000, 86 (04) : 549 - 552
[8] Total antioxidant capacity in patients with varicoceles
Meucci, E
Milardi, D
Mordente, A
Martorana, GE
Giacchi, E
De Marinis, L
Mancini, A
[J]. FERTILITY AND STERILITY, 2003, 79 : 1577 - 1583
[9] Varicocelectomy reduces reactive oxygen species levels and increases antioxidant activity of seminal plasma from infertile men with varicocele
Mostafa, T
Anis, TH
El-Nashar, A
Imam, H
Othman, IA
[J]. INTERNATIONAL JOURNAL OF ANDROLOGY, 2001, 24 (05): : 261 - 265
[10] Varicocele and male infertility: Part II - Pathophysiology of varicoceles in male infertility
Naughton, CK
Nangia, AK
Agarwal, A
[J]. HUMAN REPRODUCTION UPDATE, 2001, 7 (05) : 473 - 481

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