Caffeine's influence on nicotine's effects in nonsmokers

被引：9

作者：

Blank, Melissa D.

Kleykamp, Bethea A.

Jennings, Janine M.

Eissenberg, Thomas

机构：

[1] Virginia Commonwealth Univ, Dept Psychol, Richmond, VA 23298 USA

[2] Virginia Commonwealth Univ, Inst Drug & Alcohol Studies, Richmond, VA USA

[3] Wake Forest Univ, Dept Psychol, Winston Salem, NC 27109 USA

来源：

AMERICAN JOURNAL OF HEALTH BEHAVIOR | 2007年 / 31卷 / 05期

关键词：

nicotine; caffeine; interaction; subjective effect; cognition;

D O I：

10.5993/AJHB.31.5.3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To determine if nicotine's effects are influenced by caffeine in nonsmoking, moderate-caffeine consuming individuals (N=20). Methods: The first 3 sessions included one of 3 randomly ordered, double-blind caffeine doses (0, 75, or 150 mg, oral [po]) and 2 single-blind nicotine gum doses (2 and 4 mg) in ascending order. The fourth session (single blind) repeated the 0 mg caffeine condition. Results: Nicotine increased heart rate and subjective ratings indicative of aversive effects, and decreased reaction times. These effects were independent of caffeine dose and reliable across sessions. Conclusions: In nonsmokers, nicotine effects are not influenced by moderate caffeine doses.

引用

收藏

页码：473 / 483

页数：11

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