Use of cerium(IV) nitrate in the spectrophotometric determination of levodopa and methyldopa in the pure form and pharmaceutical preparations

被引：23

作者：

Helaleh, MIH ^{[1
]}

Rahman, N ^{[1
]}

Abu-Nameh, ESM ^{[1
]}

机构：

[1] Aligarh Muslim Univ, Dept Chem, Analyt Res Div, Aligarh 202002, Uttar Pradesh, India

来源：

ANALYTICAL SCIENCES | 1997年 / 13卷 / 06期

关键词：

levodopa; methyldopa; spectrophotometry; cerium(IV) nitrate; pharmaceutical products analysis;

D O I：

10.2116/analsci.13.1007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An accurate and simple quantitative method for determining levodopa and methyldopa is proposed. Cerium(IV) has been successively used to react with drugs in 2 M H2SO4 at 80 degrees C. The absorbance of colored products was measured at 510 and 550 nm for levodopa and methyldopa, respectively. The method has been extended to the determination of these drugs in dosage forms. The results have been statistically compared with those obtained by the reference method.

引用

页码：1007 / 1010

页数：4

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