Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2)

被引:2
作者
Akdagli, Sevtap Arikan [1 ]
Azap, Alpay [2 ]
Demirkazik, Figen Basaran [3 ]
Ener, Beyza [4 ]
Hayran, Sibel Ascioglu [5 ]
Kumbasar, Ozlem Ozdemir [6 ]
Metan, Gokhan [7 ]
Odabasi, Zekaver [8 ]
Uzun, Omrum [5 ]
Akan, Hamdi [9 ]
机构
[1] Hacettepe Univ, Fac Med, Dept Med Microbiol, Ankara, Turkey
[2] Ankara Univ, Fac Med, Dept Infect Dis & Clin Microbiol, TR-06100 Ankara, Turkey
[3] Hacettepe Univ, Fac Med, Dept Radiol, Ankara, Turkey
[4] Uludag Univ, Fac Med, Dept Microbiol, Bursa, Turkey
[5] Hacettepe Univ, Fac Med, Dept Infect Dis, Ankara, Turkey
[6] Ankara Univ, Fac Med, Dept Pulm Dis, TR-06100 Ankara, Turkey
[7] Erciyes Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Kayseri, Turkey
[8] Marmara Univ, Fac Med, Dept Infect Dis, Istanbul, Turkey
[9] Ankara Univ, Fac Med, Dept Hematol, TR-06100 Ankara, Turkey
关键词
Diagnosis; Invasive fungal infection; Imaging; Serology; BETA-D-GLUCAN; GALACTOMANNAN ENZYME-IMMUNOASSAY; BRONCHOALVEOLAR LAVAGE FLUID; LINKED-IMMUNOSORBENT-ASSAY; JOINT CLINICAL GUIDELINES; 3RD EUROPEAN CONFERENCE; PULMONARY ASPERGILLOSIS; BLOOD CULTURE; IMMUNOCOMPROMISED PATIENTS; INFECTIONS;
D O I
10.4274/tjh.2014.0218
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
One of the most problematic issues in hematological malignancies is the diagnosis of invasive fungal diseases. Especially, the difficulty of mycological diagnosis and the necessity of immediate intervention in molds have led to the adoption of "surrogate markers" that do not verify but rather strongly suggest fungal infection. The markers commonly used are galactomannan (GM), beta-glucan, and imaging methods. Although there are numerous studies on these diagnostic approaches, none of these markers serve as a support for the clinician, as is the case in human immunodeficiency virus (HIV) or cytomegalovirus (CMV) infections. This paper has been prepared to explain the diagnostic tests. As molecular tests have not been standardized and are not used routinely in the clinics, they will not be mentioned here.
引用
收藏
页码:342 / 356
页数:15
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