Vitamin A helps gut T cells find their way in the dark

被引：11

作者：

Johansson-Lindbom, B ^{[1
]}

Agace, WW ^{[1
]}

机构：

[1] Lund Univ, Dept Cell & Mol Biol, Immunol Sect, Lund, Sweden

来源：

NATURE MEDICINE | 2004年 / 10卷 / 12期

关键词：

D O I：

10.1038/nm1204-1300

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.

引用

页码：1300 / 1301

页数：2

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