Rfam: an RNA family database

被引：1137

作者：

Griffiths-Jones, S

Bateman, A

Marshall, M

Khanna, A

Eddy, SR

机构：

[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[2] Washington Univ, Sch Med, Howard Hughes Med Inst, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

来源：

NUCLEIC ACIDS RESEARCH | 2003年 / 31卷 / 01期

关键词：

D O I：

10.1093/nar/gkg006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rfam is a collection of multiple sequence alignments and covariance models representing non- coding RNA families. Rfam is available on the web in the UK at http: / / www. sanger. ac. uk/ Software/ Rfam/ and in the US at http: / / rfam. wustl. edu/. These websites allow the user to search a query sequence against a library of covariance models, and view multiple sequence alignments and family annotation. The database can also be downloaded in at le form and searched locally using the INFERNAL package ( http: / / infernal. wustl. edu/). The first release of Rfam ( 1.0) contains 25 families, which annotate over 50 000 non- coding RNA genes in the taxonomic divisions of the EMBL nucleotide database.

引用

页码：439 / 441

页数：3

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