Prognosis and clinicopathological characteristics of Ib-IIb adenocarcinoma of the uterine cervix in patients who have had radical hysterectomy

被引:105
作者
Irie, T [1 ]
Kigawa, J [1 ]
Minagawa, Y [1 ]
Itamochi, H [1 ]
Sato, S [1 ]
Akeshima, R [1 ]
Terakawa, N [1 ]
机构
[1] Tottori Univ, Sch Med, Dept Obstet & Gynecol, Yonago, Tottori 683504, Japan
来源
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY | 2000年 / 26卷 / 05期
关键词
cervical adenocarcinoma; radical hysterectomy; lymph node involvement; clinicopathological characteristics;
D O I
10.1053/ejso.1999.0923
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aims: The aim of the present study was to evaluate the outcome of patients with stage Ib-IIb cervical adenocarcinoma treated with radical hysterectomy, and to determine the clinicopathological characteristics of those patients. Methods: A total of 255 patients with cervical carcinoma stage Ib-IIb (57 adenocarcinoma and 198 squamous cell carcinoma) who had undergone radical hysterectomy were included in this study. Patient survival distribution was calculated using the Kaplan-Meier method. Results: The estimated 5-year survival rate for patients with adenocarcinoma was significantly poorer than that for patients with squamous cell carcinoma (77.9% vs 91.7%). The survival rate in stage Ib patients did not differ between two groups (95.8% vs 94.4% respectively). The incidence of lymph node involvement was significantly higher in patients with adenocarcinoma than in those with squamous cell carcinoma (31.6% vs 14.8%). Among patients receiving post-operative radiotherapy, the survival rate for adenocarcinoma (71.1%) was significantly poorer than that for squamous cell carcinoma (90.0%). When patients underwent radical hysterectomy, the survival rate for stage II patients with adenocarcinoma was significantly poorer than that for patients with squamous cell carcinoma. Conclusions: The higher incidence of lymphnode involvement and lower response to post-operative radiotherapy are considered to be factors of poorer prognosis in cervical adenocarcinoma. (C) 2000 Harcourt Publishers Ltd.
引用
收藏
页码:464 / 467
页数:4
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