Assignment of transcription factor NFAT5 to human chromosome 16q22.1, murine chromosome 8D and porcine chromosome 6p1.4 and comparison of the polyglutamine domains

被引：8

作者：

Hebinck, A

Dalski, A

Engel, H

Mattei, MG

Hawken, R

Schwinger, E

Zühlke, C

机构：

[1] Med Univ Lubeck, Inst Humangenet, D-23538 Lubeck, Germany

[2] Univ Marburg, Inst Humangenet, Marburg, Germany

[3] INSERM U4, Marseille, France

[4] Univ Minnesota, Dept Vet Pathobiol, St Paul, MN 55108 USA

来源：

CYTOGENETICS AND CELL GENETICS | 2000年 / 90卷 / 1-2期

关键词：

D O I：

10.1159/000015665

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

To date, transcription factors of the NFAT family (nuclear factors of activated T cells) have been described for mouse and man. Recently, we mapped the human NFAT5 gene to chromosome 16 by PCR using DNA from hybrid cell lines. Here we report the exact position of the human gene between D16S496 and W15254 within the 16q22.1 subband, the localization of the murine gene at chromosome 8D, and the identification and mapping of the porcine counterpart to chromosome 6p1.4. Copyright (C) 2000 S. Karger AG, Basel.

引用

收藏

页码：68 / 70

页数：3

相关论文

共 14 条

[1] TRANSCRIPTIONAL ACTIVATION MODULATED BY HOMOPOLYMERIC GLUTAMINE AND PROLINE STRETCHES [J].

GERBER, HP ;

SEIPEL, K ;

GEORGIEV, O ;

HOFFERER, M ;

HUG, M ;

RUSCONI, S ;

SCHAFFNER, W .

SCIENCE, 1994, 263 (5148) :808-811

[2] A first-generation porcine whole-genome radiation hybrid map [J].

Hawken, RJ ;

Murtaugh, J ;

Flickinger, GH ;

Yerle, M ;

Robic, A ;

Milan, D ;

Gellin, J ;

Beattie, CW ;

Schook, LB ;

Alexander, LJ .

MAMMALIAN GENOME, 1999, 10 (08) :824-830

[3] A SIMPLE METHOD FOR SIMULTANEOUS R-BANDING OR G-BANDING AND FLUORESCENCE INSITU HYBRIDIZATION OF SMALL SINGLE-COPY GENES [J].

LEMIEUX, N ;

DUTRILLAUX, B ;

VIEGASPEQUIGNOT, E .

CYTOGENETICS AND CELL GENETICS, 1992, 59 (04) :311-312

[4]

Limprasert P, 1997, AM J MED GENET, V74, P488, DOI 10.1002/(SICI)1096-8628(19970919)74:5<488::AID-AJMG6>3.0.CO

[5]

2-K

[6] NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun [J].

López-Rodríguez, C ;

Aramburu, J ;

Rakeman, AS ;

Rao, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (13) :7214-7219

[7]

Nagase T, 1998, DNA Res, V5, P355, DOI 10.1093/dnares/5.6.355

[8] THE MURINE HOMOLOGS OF THE HUNTINGTON DISEASE GENE (HDH) AND THE ALPHA-ADDUCIN GENE (ADD1) MAP TO MOUSE CHROMOSOME-5 WITHIN A REGION OF CONSERVED SYNTENY WITH HUMAN-CHROMOSOME 4P16.3 [J].

NASIR, J ;

LIN, BY ;

BUCAN, M ;

KOIZUMI, T ;

NADEAU, JH ;

HAYDEN, MR .

GENOMICS, 1994, 22 (01) :198-201

[9] POLAR ZIPPERS - THEIR ROLE IN HUMAN-DISEASE [J].

PERUTZ, M .

PROTEIN SCIENCE, 1994, 3 (10) :1629-1637

[10] CYTOGENETIC ANALYSIS USING QUANTITATIVE, HIGH-SENSITIVITY, FLUORESCENCE HYBRIDIZATION [J].

PINKEL, D ;

STRAUME, T ;

GRAY, JW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (09) :2934-2938