Controlling the intrachain segregation on a single DNA molecule

被引：42

作者：

Zinchenko, AA

Sergeyev, VG

Murata, S ^{[1
]}

Yoshikawa, K

机构：

[1] Nagoya Univ, Grad Sch Environm Studies, Nagoya, Aichi 4648601, Japan

[2] Nagoya Univ, CREST, JST, Sch Informat & Sci, Nagoya, Aichi 4648601, Japan

[3] Moscow MV Lomonosov State Univ, Dept Polymer Sci, Fac Chem, Moscow 119899, Russia

[4] Kyoto Univ, Dept Phys, Kyoto 6088501, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 15期

关键词：

D O I：

10.1021/ja028804x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intrachain segregation in single DNA molecules induced by quaternary ammonium dications was studied. By means of fluorescent and electron microscopy, it was found that variations in the chemical structure of condensing agents provide one with the opportunity to control the average amount of intrachain segregation centers on the DNA single chain. The manner of interaction between the diammonium molecules was considered to be the key factor for controlling the morphology of the partially collapsed DNA molecules. Copyright © 2003 American Chemical Society.

引用

页码：4414 / 4415

页数：2

共 27 条

[1] CONDENSATION OF DNA BY TRIVALENT CATIONS .1. EFFECTS OF DNA LENGTH AND TOPOLOGY ON THE SIZE AND SHAPE OF CONDENSED PARTICLES [J].