Pathophysiology of trigeminal neuralgia: new evidence from a trigeminal ganglion intraoperative microneurographic recording - Case report

被引:24
作者
Burchiel, KJ [1 ]
Baumann, TK [1 ]
机构
[1] Oregon Hlth Sci Univ, Dept Neurol Surg, Portland, OR 97239 USA
关键词
pain; trigeminal neuralgia; trigeminal ganglion; nerve action potential discharge; peripheral nervous system;
D O I
10.3171/jns.2004.101.5.0872
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The origin of trigeminal neuralgia (TN) appears to be vascular compression of the trigeminal nerve at the root entry zone; however, the physiological mechanism of this disorder remains uncertain. The authors obtained intraoperative microneurographic recordings from trigeminal ganglion neurons in a patient with TN immediately before percutaneous radiofrequency-induced gangliolysis. Their findings are consistent with the idea that the pain of TN is generated, at least in part, by an abnormal discharge within the peripheral nervous system.
引用
收藏
页码:872 / 873
页数:2
相关论文
共 10 条
[1]
A method for intraoperative microneurographic recording of unitary activity in the trigeminal ganglion of patients with trigeminal neuralgia [J].
Baumann, TK ;
Burchiel, KJ .
JOURNAL OF NEUROSCIENCE METHODS, 2004, 132 (01) :19-24
[2]
Pathophysiology of trigeminal neuralgia: The ignition hypothesis [J].
Devor, M ;
Amir, R ;
Rappaport, ZH .
CLINICAL JOURNAL OF PAIN, 2002, 18 (01) :4-13
[3]
IDIOPATHIC TRIGEMINAL NEURALGIA - SENSORY FEATURES AND PAIN MECHANISMS [J].
DUBNER, R ;
SHARAV, Y ;
GRACELY, RH ;
PRICE, DD .
PAIN, 1987, 31 (01) :23-33
[4]
Trigeminal neuralgia and other neuropathic pain syndromes of the head and face [J].
Elias W.J. ;
Burchiel K.J. .
Current Pain and Headache Reports, 2002, 6 (2) :115-124
[5]
FROMM GH, 1991, TRIGEMINAL NEURALGIA, P230
[6]
MECHANORECEPTOR ACTIVITY FROM THE HUMAN-FACE AND ORAL-MUCOSA [J].
JOHANSSON, RS ;
TRULSSON, M ;
OLSSON, KA ;
WESTBERG, KG .
EXPERIMENTAL BRAIN RESEARCH, 1988, 72 (01) :204-208
[7]
THE MECHANISM OF THE PAIN IN TRIGEMINAL NEURALGIA [J].
KUGELBERG, E ;
LINDBLOM, U .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1959, 22 (01) :36-43
[8]
LOW-THRESHOLD MECHANORECEPTIVE AND NOCICEPTIVE UNITS WITH UNMYELINATED (C) FIBERS IN THE HUMAN SUPRAORBITAL NERVE [J].
NORDIN, M .
JOURNAL OF PHYSIOLOGY-LONDON, 1990, 426 :229-240
[9]
TRIGEMINAL NEURALGIA - THE ROLE OF SELF-SUSTAINING DISCHARGE IN THE TRIGEMINAL GANGLION [J].
RAPPAPORT, ZH ;
DEVOR, M .
PAIN, 1994, 56 (02) :127-138
[10]
ZAKRZEWSKA JM, 1995, TRIGEMINAL NEURALGIA, P229