Single-trial analysis of oddball event-related potentials in simultaneous EEG-fMRI

被引:119
作者
Benar, Christian-G.
Schon, Daniele
Grimault, Stephan
Nazarian, Bruno
Burle, Boris
Roth, Muriel
Badier, Jean-Michel
Marquis, Patrick
Liegeois-Chauvel, Catherine
Anton, Jean-Luc
机构
[1] Fac Med Timone, INSERM, U751, F-13385 Marseille 05, France
[2] CNRS, IFR131, Ctr IRMF Marseille, Marseille, France
[3] CNRS, UMR6193, Marseille, France
[4] CNRS, UMR6155, Marseille, France
关键词
simultaneous EEG-fMRI; auditory oddball; evoked potentials; single-trial analysis; TRIGGERED FUNCTIONAL MRI; VISUAL-EVOKED POTENTIALS; BRAIN ACTIVITY; P300; AMPLITUDE; LOCALIZATION; HABITUATION; ACQUISITION; ACTIVATION; DYNAMICS; ARTIFACT;
D O I
10.1002/hbm.20289
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
There has recently been a growing interest in the use of simultaneous electroencephalography (EEG) and functional MRI (fMRI) for evoked activity in cognitive paradigms, thereby obtaining functional datasets with both high spatial and temporal resolution. The simultaneous recording permits obtaining event-related potentials (ERPs) and MR images in the same environment, conditions of stimulation, and subject state; it also enables tracing the joint fluctuations of EEG and fMRI signals. The goal of this study was to investigate the possibility of tracking the trial-to-trial changes in event-related EEG activity, and of using this information as a parameter in fMR1 analysis. We used an auditory oddball paradigm and obtained single-trial amplitude and latency features from the EEG acquired during fMRI scanning. The single-trial P300 latency presented significant correlation with parameters external to the EEG (target-to-target interval and reaction time). Moreover, we obtained significant fMRI activations for the modulation by P300 amplitude and latency, both at the single-subject and at the group level. Our results indicate that, in line with other studies, the EEG can bring a new dimension to the field of fMRI analysis by providing fine temporal information on the fluctuations in brain activity.
引用
收藏
页码:602 / 613
页数:12
相关论文
共 67 条
[1]   fMRI activation in continuous and spike-triggered EEG-fMRI studies of epileptic spikes [J].
Al-Asmi, A ;
Bénar, CG ;
Gross, DW ;
Khani, YA ;
Andermann, F ;
Pike, B ;
Dubeau, F ;
Gotman, J .
EPILEPSIA, 2003, 44 (10) :1328-1339
[2]   Identification of EEG events in the MR scanner: The problem of pulse artifact and a method for its subtraction [J].
Allen, PJ ;
Polizzi, G ;
Krakow, K ;
Fish, DR ;
Lemieux, L .
NEUROIMAGE, 1998, 8 (03) :229-239
[3]   A method for removing imaging artifact from continuous EEG recorded during functional MRI [J].
Allen, PJ ;
Josephs, O ;
Turner, R .
NEUROIMAGE, 2000, 12 (02) :230-239
[4]   Visual evoked potentials recovered from fMRI scan periods [J].
Becker, R ;
Ritter, P ;
Moosmann, M ;
Villringer, A .
HUMAN BRAIN MAPPING, 2005, 26 (03) :221-230
[5]   Quality of EEG in simultaneous EEG-fMRI for epilepsy [J].
Bénar, CG ;
Aghakhani, Y ;
Wang, YH ;
Izenberg, A ;
Al-Asmi, A ;
Dubeau, F ;
Gotman, J .
CLINICAL NEUROPHYSIOLOGY, 2003, 114 (03) :569-580
[6]  
BENKHERRAT M, 2005, P EUROCON 2005
[7]   Influence of EEG electrodes on the BOLD fMRI signal [J].
Bonmassar, G ;
Hadjikhani, N ;
Ives, JR ;
Hinton, D ;
Belliveau, JW .
HUMAN BRAIN MAPPING, 2001, 14 (02) :108-115
[8]   Visual evoked potential (VEP) measured by simultaneous 64-channel EEG and 3T fMRI [J].
Bonmassar, G ;
Anami, K ;
Ives, J ;
Belliveau, JW .
NEUROREPORT, 1999, 10 (09) :1893-1897
[9]  
BRANDEIS D, 2003, P 9 ANN M ORG HUM BR
[10]   Neuronal chronometry of target detection: Fusion of hemodynamic and event-related potential data [J].
Calhoun, VD ;
Adali, T ;
Pearlson, GD ;
Kiehl, KA .
NEUROIMAGE, 2006, 30 (02) :544-553