Sex ratio and time to pregnancy: analysis of four large European population surveys

被引:19
作者
Joffe, Mike [1 ]
Bennett, James
Best, Nicky
Jensen, Tina Kold
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Publ Hlth, London W2 1PG, England
[2] Univ So Denmark, Inst Publ Hlth, Odense, Denmark
来源
BMJ-BRITISH MEDICAL JOURNAL | 2007年 / 334卷 / 7592期
基金
英国医学研究理事会;
关键词
D O I
10.1136/bmj.39097.508426.BE
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys. Setting Denmark and the United Kingdom. Participants 49 506 pregnancies. Main outcome measure Secondary sex ratio. Results No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category. Conclusion No association was found between the secondary sex ratio and time to pregnancy.
引用
收藏
页码:524 / 526A
页数:6
相关论文
共 24 条
[1]  
Armstrong BK., 1995, PRINCIPLES EXPOSURE
[2]   APPROXIMATE INFERENCE IN GENERALIZED LINEAR MIXED MODELS [J].
BRESLOW, NE ;
CLAYTON, DG .
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1993, 88 (421) :9-25
[3]  
*COMM TOX CHEM FOO, 2001, STAT TOL DAIL INT DI
[4]   Reduced ratio of male to female births in several industrial countries - A sentinel health indicator? [J].
Davis, DL ;
Gottlieb, MB ;
Stampnitzky, JR .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (13) :1018-1023
[5]  
DECOCK J, 1995, OCCUP ENVIRON MED, V52, P429
[6]  
FRANCE JT, 1992, INT J FERTIL, V37, P244
[7]   Fertility and offspring sex ratio of men who develop testicular cancer:: a record linkage study [J].
Jacobsen, R ;
Bostofte, E ;
Engholm, G ;
Hansen, J ;
Skakkebæk, NE ;
Moller, H .
HUMAN REPRODUCTION, 2000, 15 (09) :1958-1961
[8]   Offspring sex ratio of subfertile men and men with abnormal sperm characteristics [J].
Jacobsen, R ;
Bostofte, E ;
Skakkebaek, NE ;
Hansen, J ;
Moller, H .
HUMAN REPRODUCTION, 2000, 15 (11) :2369-2370
[9]   Male reproductive hazards and occupation [J].
James, WH .
LANCET, 1996, 347 (9003) :773-773
[10]   Selection bias in determining the age dependence of waiting time to pregnancy [J].
Jensen, TK ;
Scheike, T ;
Keiding, N ;
Schaumburg, I ;
Grandjean, P .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2000, 152 (06) :565-572