Evolution of the protein repertoire

被引：406

作者：

Chothia, C

Gough, J

Vogel, C

Teichmann, SA

机构：

[1] MRC, Mol Biol Lab, Struct Studies Div, Cambridge CB2 2QH, England

[2] Stanford Univ, Sch Med, Dept Biol Struct, Stanford, CA 94305 USA

来源：

SCIENCE | 2003年 / 300卷 / 5626期

关键词：

D O I：

10.1126/science.1085371

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.

引用

页码：1701 / 1703

页数：3

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