Age-dependent accuracy of Helicobacter pylori antibody assays for adults, with special emphasis on atrophic gastritis

被引：15

作者：

Salomaa-Räsänen, A

Kosunen, TU

Mattila, J

Sarna, S

Rautelin, H

机构：

[1] Univ Helsinki, Dept Bacteriol & Immunol, Haartman Inst, FIN-00014 Helsinki, Finland

[2] Univ Helsinki, Dept Publ Hlth, Helsinki, Finland

[3] Univ Helsinki, Cent Hosp, Dept Microbiol, HUSLAB, Helsinki, Finland

[4] Vammala Hlth Ctr, Vammala, Finland

[5] Tampere Univ Hosp, Dept Pathol, Tampere, Finland

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2004年 / 11卷 / 06期

关键词：

D O I：

10.1128/CDLI.11.6.1185-1188.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The accuracy of Helicobacter pylori antibody assays for 561 consecutive adult outpatients who had undergone gastroscopy was studied. The sensitivity of an immunoglobulin G test was 99 to 100% for all age groups, but the specificity declined by age group, from 99% for those aged 15 to 49 years to 75% for those aged greater than or equal to65 years. The exclusion of false-positive results for patients with atrophic gastritis improved the specificity to 93 to 97% for the older age groups.

引用

页码：1185 / 1188

页数：4

共 24 条

[1]

Blaser MJ, 2004, J CLIN INVEST, V113, P321, DOI [10.1172/JCI200420925, 10.1172/JCI20925]

[2]

Chey WD, 1996, AM J GASTROENTEROL, V91, P89

[3] MULTILABORATORY COMPARISON OF 8 COMMERCIALLY AVAILABLE HELICOBACTER-PYLORI SEROLOGY KITS [J].