A moment closure model for sexually transmitted disease transmission through a concurrent partnership network

被引:55
作者
Bauch, C [1 ]
Rand, DA [1 ]
机构
[1] Univ Warwick, Inst Math, Coventry CV4 7AL, W Midlands, England
关键词
concurrency; moment closure; sexually transmitted diseases; sexual networks; correlation equations;
D O I
10.1098/rspb.2000.1244
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A moment closure model of sexually transmitted disease spread through a concurrent partnership network is developed. The model employs pair approximations of higher-order correlations to derive equations of motion in terms of numbers of pairs and singletons. The model is derived from an underlying stochastic process of partnership network formation and disease transmission. The model is analysed numerically and the final size and time evolution are considered for various levels of concurrency as measured by the concurrency index kappa(3) of Kretzschmar and Morris. Additionally, a new way of calculating R-0 for spatial network models is developed. It is found that concurrency significantly increases R-0 and the final size of a sexually transmitted disease, with some interesting exceptions.
引用
收藏
页码:2019 / 2027
页数:9
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