A model of disease and vaccination for infections with acute and chronic phases

被引:20
作者
Reade, B
Bowers, RG
Begon, M
Gaskell, R
机构
[1] Univ Liverpool, Sch Biol Sci, Dept Math Sci, Liverpool L69 3BX, Merseyside, England
[2] Univ Liverpool, Sch Biol Sci, Populat Biol Res Grp, Liverpool L69 3BX, Merseyside, England
[3] Univ Liverpool, Ctr Comparat Infect Dis, Dept Vet Pathol, Liverpool L69 3BX, Merseyside, England
基金
英国惠康基金;
关键词
D O I
10.1006/jtbi.1997.0557
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A general model is presented of a disease in which both recovered and vaccinated individuals are protected from acute disease, but are still susceptible to chronic infection. The special threshold conditions for the establishment and persistence of such a disease are derived and explained in full. The efficacies of alternative vaccination strategies are detailed and a specific example of such a disease is given by examining feline calicivirus (FCV), a cause of upper respiratory tract disease in cats. (C) 1998 Academic Press Limited.
引用
收藏
页码:355 / 367
页数:13
相关论文
共 16 条
[1]  
ANDERSON R M, 1991
[2]   Community structure and the interplay between interspecific infection and competition [J].
Bowers, RG ;
Turner, J .
JOURNAL OF THEORETICAL BIOLOGY, 1997, 187 (01) :95-109
[3]  
COUTTS AJ, 1994, VET REC, V135, P555
[4]   INVESTIGATION OF VACCINE REACTIONS AND BREAKDOWNS AFTER FELINE CALICIVIRUS VACCINATION [J].
DAWSON, S ;
MCARDLE, F ;
BENNETT, D ;
CARTER, SD ;
BENNETT, M ;
RYVAR, R ;
GASKELL, RM .
VETERINARY RECORD, 1993, 132 (14) :346-350
[5]   EFFECT OF PRIMARY-STAGE FELINE IMMUNODEFICIENCY VIRUS-INFECTION ON SUBSEQUENT FELINE CALCIVIRUS VACCINATION AND CHALLENGE IN CATS [J].
DAWSON, S ;
SMYTH, NR ;
BENNETT, M ;
GASKELL, RM ;
MCCRACKEN, CM ;
BROWN, A ;
GASKELL, CJ .
AIDS, 1991, 5 (06) :747-750
[6]  
DIEKMANN O, 1990, J MATH BIOL, V28, P365
[7]  
GASKELL RM, 1994, FELINE MED THERAPEUT, P453
[8]   ISOLATION OF FELINE CALICIVIRUS AND FELINE HERPESVIRUS FROM DOMESTIC CATS 1980 TO 1989 [J].
HARBOUR, DA ;
HOWARD, PE ;
GASKELL, RM .
VETERINARY RECORD, 1991, 128 (04) :77-80
[9]  
Heesterbeek J. A. P., 1995, P90, DOI 10.1017/CBO9780511629396.004
[10]  
Kitching R. P., 1992, State Veterinary Journal, V2, P7