Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade

被引：34

作者：

Dorrestein, PC

Poole, K

Begley, TP ^{[1
]}

机构：

[1] Cornell Univ, Dept Chem & Chem Biol, Baker Lab 120, Ithaca, NY 14853 USA

[2] Queens Univ, Dept Microbiol & Immunol, Kingston, ON K7L 3N6, Canada

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 13期

关键词：

D O I：

10.1021/ol034531e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The pyoverdine chromophore is formed in a reaction involving a two-electron oxidation, a conjugate addition, and a second two-electron oxidation. This oxidative cascade can be carried out with polyphenol oxidase (PPO), MnO2, and cell-free extracts from Pseudomonas aeruginosa.

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收藏

页码：2215 / 2217

页数：3

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