Total synthesis of naturally occurring prostaglandin F2α on a non-cross-linked polystyrene support

被引：52

作者：

Chen, SQ

Janda, KD

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(98)00729-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the naturally occurring prostaglandin F-2 alpha (PGF(2 alpha)) was achieved on a soluble non-cross-linked polystyrene support (NCPS). The approach was predicated upon a three component coupling scheme that is both synthetically flexible and convergent in nature. The methodology detailed should provide access to libraries of the PGF series. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3943 / 3946

页数：4

共 18 条

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