An efficient method for the conversion of aromatic and aliphatic nitriles to the corresponding N-tert-butyl amides:: a modified Ritter reaction

被引：77

作者：

Reddy, KL ^{[1
]}

机构：

[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Proc Res & Dev, Wallingford, CT 06492 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 07期

关键词：

modified Ritter reaction; nitriles; tert-butyl acetate; N-tert-butyl amides;

D O I：

10.1016/S0040-4039(03)00006-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic and aliphatic nitriles react with tert-butyl acetate in the presence of a catalytic amount of sulfuric acid to give the corresponding N-tert-butyl amides in excellent yields. (C) 2003 Published by Elsevier Science Ltd.

引用

页码：1453 / 1455

页数：3

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