Diversity and dynamics of dendritic signaling

被引:602
作者
Häusser, M
Spruston, N
Stuart, GJ
机构
[1] UCL, Dept Physiol, London WC1E 6BT, England
[2] Northwestern Univ, Inst Neurosci, Dept Neurobiol & Physiol, Evanston, IL 60208 USA
[3] Australian Natl Univ, John Curtin Sch Med Res, Div Neurosci, Canberra, ACT 0200, Australia
关键词
D O I
10.1126/science.290.5492.739
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Communication between neurons in the brain occurs primarily through synapses made onto elaborate treelike structures called dendrites. New electrical and optical recording techniques have Led to tremendous advances in our understanding of how dendrites contribute to neuronal computation in the mammalian brain. The varied morphology and electrical and chemical properties of dendrites enable a spectrum of local and Long-range signaling, defining the input-output relationship of neurons and the rules for induction of synaptic plasticity. In this way, diversity in dendritic signaling allows individual neurons to carry out specialized functions within their respective networks.
引用
收藏
页码:739 / 744
页数:8
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