Optical traps: shedding light on biological processes

被引:9
作者
Allaway, D [1 ]
Schofield, NA [1 ]
Poole, PS [1 ]
机构
[1] Univ Reading, Sch Anim & Microbial Sci, Reading RG6 6AH, Berks, England
关键词
biomechanical force; microdissection; micromanipulation; optical trap;
D O I
10.1023/A:1005647711606
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Optical traps exploit the radiation forces of laser light to manipulate microscopic particles. The ability to manipulate biological material and quantify the force required has been exploited in the biosciences; from the isolation of single cells to kinetic measurements of single motor molecules. This review describes the theory of optical trapping and using recent publications gives examples of how it has been employed across a broad spectrum of biological research.
引用
收藏
页码:887 / 892
页数:6
相关论文
共 38 条
  • [1] Tying a molecular knot with optical tweezers
    Arai, Y
    Yasuda, R
    Akashi, K
    Harada, Y
    Miyata, H
    Kinosita, K
    Itoh, H
    [J]. NATURE, 1999, 399 (6735) : 446 - 448
  • [2] Optical trapping and manipulation of neutral particles using lasers
    Ashkin, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) : 4853 - 4860
  • [3] OPTICAL TRAPPING AND MANIPULATION OF VIRUSES AND BACTERIA
    ASHKIN, A
    DZIEDZIC, JM
    [J]. SCIENCE, 1987, 235 (4795) : 1517 - 1520
  • [4] FORCE GENERATION OF ORGANELLE TRANSPORT MEASURED INVIVO BY AN INFRARED-LASER TRAP
    ASHKIN, A
    SCHUTZE, K
    DZIEDZIC, JM
    EUTENEUER, U
    SCHLIWA, M
    [J]. NATURE, 1990, 348 (6299) : 346 - 348
  • [5] OPTICAL TRAPPING AND MANIPULATION OF SINGLE CELLS USING INFRARED-LASER BEAMS
    ASHKIN, A
    DZIEDZIC, JM
    YAMANE, T
    [J]. NATURE, 1987, 330 (6150) : 769 - 771
  • [6] INTERNAL CELL MANIPULATION USING INFRARED-LASER TRAPS
    ASHKIN, A
    DZIEDZIC, JM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) : 7914 - 7918
  • [7] Berns MW, 1998, METHOD CELL BIOL, V55, P71
  • [8] COMPLIANCE OF BACTERIAL FLAGELLA MEASURED WITH OPTICAL TWEEZERS
    BLOCK, SM
    BLAIR, DF
    BERG, HC
    [J]. NATURE, 1989, 338 (6215) : 514 - 518
  • [9] A new method to study shape recovery of red blood cells using multiple optical trapping
    Bronkhorst, PJH
    Streekstra, GJ
    Grimbergen, J
    Nijhof, EJ
    Sixma, JJ
    Brakenhoff, GJ
    [J]. BIOPHYSICAL JOURNAL, 1995, 69 (05) : 1666 - 1673
  • [10] GREEN FLUORESCENT PROTEIN AS A MARKER FOR GENE-EXPRESSION
    CHALFIE, M
    TU, Y
    EUSKIRCHEN, G
    WARD, WW
    PRASHER, DC
    [J]. SCIENCE, 1994, 263 (5148) : 802 - 805