Telomeres and senescence: The history, the experiment, the future

被引:141
作者
Greider, CW [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Genet & Mol Biol, Baltimore, MD 21205 USA
关键词
D O I
10.1016/S0960-9822(98)70105-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Telomere length has been proposed to signal entry into cellular senescence. Expression of the human telomerase subunit, hTERT, in primary cells now shows that these cells bypass senescence.
引用
收藏
页码:R178 / +
页数:5
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