High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis

被引:80
作者
Ulloa, L [1 ]
Batliwalla, FM [1 ]
Andersson, U [1 ]
Gregersen, PK [1 ]
Tracey, KJ [1 ]
机构
[1] N Shore Univ Hosp, Long Isl Jewish Res Inst, Manhasset, NY 11030 USA
来源
ARTHRITIS AND RHEUMATISM | 2003年 / 48卷 / 04期
关键词
BASIC AMINO-ACIDS; NEURITE OUTGROWTH; BINDING PROTEIN; AMPHOTERIN; HMG-1; MICE; INFLAMMATION; ANTIBODIES; MEDIATOR; CELLS;
D O I
10.1002/art.10854
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:876 / 881
页数:6
相关论文
共 30 条
[1]   Cutting edge: HMG-1 as a mediator of acute lung inflammation [J].
Abraham, E ;
Arcaroli, J ;
Carmody, A ;
Wang, HC ;
Tracey, KJ .
JOURNAL OF IMMUNOLOGY, 2000, 165 (06) :2950-2954
[2]   HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion [J].
Agnello, D ;
Wang, HC ;
Yang, H ;
Tracey, KJ ;
Ghezzi, P .
CYTOKINE, 2002, 18 (04) :231-236
[3]   High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes [J].
Andersson, U ;
Wang, HC ;
Palmblad, K ;
Aveberger, AC ;
Bloom, O ;
Erlandsson-Harris, H ;
Janson, A ;
Kokkola, R ;
Zhang, MH ;
Yang, H ;
Tracey, KJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (04) :565-570
[4]  
AYER LM, 1994, J RHEUMATOL, V21, P2071
[5]   A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis [J].
Baugh, JA ;
Chitnis, S ;
Donnelly, SC ;
Monteiro, J ;
Lin, X ;
Plant, BJ ;
Wolfe, F ;
Gregersen, PK ;
Bucala, R .
GENES AND IMMUNITY, 2002, 3 (03) :170-176
[6]   Upwardly mobile proteins Workshop: The role of HMG proteins in chromatin structure, gene expression and neoplasia [J].
Bianchi, Marco E. ;
Beltrame, Monica .
EMBO REPORTS, 2000, 1 (02) :109-114
[7]   Revised nomenclature for high mobility group (HMG) chromosomal proteins [J].
Bustin, M .
TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (03) :152-153
[8]   The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice [J].
Calogero, S ;
Grassi, F ;
Aguzzi, A ;
Voigtländer, T ;
Ferrier, P ;
Ferrari, S ;
Bianchi, ME .
NATURE GENETICS, 1999, 22 (03) :276-280
[9]   The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells [J].
Degryse, B ;
Bonaldi, T ;
Scaffidi, P ;
Müller, S ;
Resnati, M ;
Sanvito, F ;
Arrigoni, G ;
Bianchi, ME .
JOURNAL OF CELL BIOLOGY, 2001, 152 (06) :1197-1206
[10]   The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway [J].
Gardella, S ;
Andrei, C ;
Ferrera, D ;
Lotti, LV ;
Torrisi, MR ;
Bianchi, ME ;
Rubartelli, A .
EMBO REPORTS, 2002, 3 (10) :995-1001