Prevalence of three prothrombotic polymorphisms:: Factor V G1691A, factor II G20210A and methylenetetrahydrofolate reductase (MTHFR) C 677T in Argentina

被引:19
作者
Genoud, V
Castañon, M
Annichino-Bizzacchi, J
Korin, J
Kordich, L
机构
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Biol, Lab Hemostasia & Trombosis, RA-1053 Buenos Aires, DF, Argentina
[2] State Univ Campinas, Hematol Hemotherapy Ctr, Campinas, SP, Brazil
关键词
thrombophilia; Factor V Leiden; prothrombin; 20210; MTHFR; prevalence;
D O I
10.1016/S0049-3848(00)00314-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Screening in selected but still wide populations such as women with recurrent fetal loss, placental insufficiency, pre-eclampsia, or needing oral contraception, or programmed high-risk surgery in both sexes, is still controversial. Knowledge of the prevalence of these polymorphisms in the general population is useful in order to take desicions that could considerably increase the burden to health resources, even in developed countries.
引用
收藏
页码:127 / 131
页数:5
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