Guidelines for antithrombotic therapy in pediatric patients

被引：86

作者：

Andrew, M

Michelson, AD

Bovill, E

Leaker, M

Massicotte, MP

机构：

[1] Hamilton Civ Hosp, Res Ctr, Henderson Gen Div, Hamilton, ON L8V 1C3, Canada

[2] Hosp Sick Children, Toronto, ON M5G 1X8, Canada

[3] Univ Massachusetts, Sch Med, Ctr Platelet Funct Studies, Dept Pediat, Worcester, MA 01605 USA

[4] Univ Vermont, Coll Med, Dept Pathol, Burlington, VT 05405 USA

来源：

JOURNAL OF PEDIATRICS | 1998年 / 132卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0022-3476(98)70343-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Because of the relatively low incidence of TEs in children, the diagnostic and therapeutic approaches used are largely extrapolated from guidelines for adults. Features that differ in children compared with adults include underlying disorders, high incidence of CVL-related DVT in the upper venous system, and response to SH, warfarin, and thrombolytic agents. There is a paucity of information on the risk/benefit ratio of the therapeutic interventions and long-term outcome. Clinical trials are urgently needed to clarify optimal management for pediatric patients with TEs.

引用

页码：575 / 588

页数：14

共 148 条

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