Stachybotrys

被引:17
作者
Etzel, RA [1 ]
机构
[1] George Washington Univ, Sch Pub Hlth & Hlth Serv, Div Occupat & Environm Hlth, Washington, DC USA
关键词
D O I
10.1097/00008480-200302000-00017
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Stachybotrys is a toxin-producing fungus that grows indoors when both water and cellulose are available. Epidemiologic evidence has demonstrated an association between acute pulmonary hemorrhage in infants and exposure to Stachybotrys and other fungi in water-damaged home environments. In recent years, advances in understanding of this association have occurred in six major areas: animal models, biologic mechanism of lung injury, dose-response relationship, isolation from diseased patients, detection methods, and intervention. The association demonstrates strength, consistency, coherence, and specificity. While additional data are gathered, a preventive approach to reducing the exposure of infants with pulmonary hemorrhage is suggested. Curr Opin Pediatr 2003,15:103-106 (C) 2003 Lippincott Williams Wilkins, Inc.
引用
收藏
页码:103 / 106
页数:4
相关论文
共 44 条
[1]  
ANDRASSY K, 1980, MYKOSEN, V23, P130
[2]  
[Anonymous], 1980, Foundations of epidemiology
[3]  
*CDC, 2002, PULM HEM HEM INF
[4]  
CREASIA DA, 1989, TRICHOTHECENE MYCOTO, V1, P181
[5]   AIRBORNE OUTBREAK OF TRICHOTHECENE TOXICOSIS [J].
CROFT, WA ;
JARVIS, BB ;
YATAWARA, CS .
ATMOSPHERIC ENVIRONMENT, 1986, 20 (03) :549-552
[6]   Clinical profile of 30 infants with acute pulmonary hemorrhage in Cleveland [J].
Dearborn, DG ;
Smith, PG ;
Dahms, BB ;
Allan, TM ;
Sorenson, WG ;
Montana, E ;
Etzel, RA .
PEDIATRICS, 2002, 110 (03) :627-637
[7]   Overview of investigations into pulmonary hemorrhage among infants in Cleveland, Ohio [J].
Dearborn, DG ;
Yike, I ;
Sorenson, WG ;
Miller, MJ ;
Etzel, RA .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1999, 107 :495-499
[8]  
Dietrich R, 1999, BIOAEROSOLS FUNGI MY, P482
[9]  
Drobotko V. G., 1945, AMER REV SOVIET MED, V2, P238
[10]   Isolation of Stachybotrys from the lung of a child with pulmonary hemosiderosis [J].
Elidemir, O ;
Colasurdo, GN ;
Rossmann, SN ;
Fan, LL .
PEDIATRICS, 1999, 104 (04) :964-966