The theoretical and experimental studies were carried out for statistical characteristics of photon paths in strongly scattering media dependently on type of inhomogeneities, boundary conditions and method of measurements (time-gating and frequency-domain). The possibility to represent the signal perturbations due to the macroinhomogeneities as an integral along the mean photon path is used to solve the tomography reconstruction problem in terms of volume quantization. The optimum quantization scale if chosen on the basis of area across which the macroinhomogeneity characteristics are averaged.