Immune responses in tuberculosis

被引：96

作者：

Flynn, JL

Ernst, JD

机构：

[1] Univ Pittsburgh, Sch Med, Dept Mol Genet & Biochem, Pittsburgh, PA 15261 USA

[2] Univ Calif San Francisco, San Francisco Gen Hosp, Div Infect Dis, Dept Med, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(00)00116-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The initial interaction of Mycobacterium tuberculosis with phagocytes through Toll-like receptors can affect induction of the adaptive response by inflammatory cytokine production, as well as begin the process of bacterial containment by induction of antimycobacterial functions. Advances in T cell research in tuberculosis include identification of antigens recognized by CD8(+) T cells in infected hosts, elucidation of antimycobacterial mechanisms of T cells and the discovery of CD8(+) T cells that recognize antigens presented by a variety of non-classical molecules.

引用

页码：432 / 436

页数：5

共 37 条

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