Detection of low-avidity immunoglobulin G in oral fluid samples: New approach for rubella diagnosis and surveillance

被引：9

作者：

Akingbade, D ^{[1
]}

Cohen, BJ ^{[1
]}

Brown, DWG ^{[1
]}

机构：

[1] Cent Publ Hlth Lab, Enter Resp & Neurol Virus Lab, London NW9 5HT, England

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2003年 / 10卷 / 01期

关键词：

D O I：

10.1128/CDLI.10.1.189-190.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Low-avidity rubella immunoglobulin G (IgG) was detected in oral fluid samples from 30 of 32 rubella IgM-positive patients (sensitivity, 94%) and from 4 of 34 IgM-negative patients (specificity, 88%). Measuring IgG avidity in oral fluid samples could improve the reliability of rubella surveillance when the incidence of the disease and the positive predictive value of IgM tests are low.

引用

页码：189 / 190

页数：2

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