Detection of human coronavirus NL63 in young children with bronchiolitis

被引：80

作者：

Ebihara, T ^{[1
]}

Endo, R ^{[1
]}

Ma, XM ^{[1
]}

Ishiguro, N ^{[1
]}

Kikuta, H ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Med, Dept Pediat, Kita Ku, Sapporo, Hokkaido 0608638, Japan

来源：

JOURNAL OF MEDICAL VIROLOGY | 2005年 / 75卷 / 03期

关键词：

HCoV-NL63; acute bronchiolitis; acute laryngotracheobronchitis;

D O I：

10.1002/jmv.20289

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

HCoV-NL63, the fourth human coronavirus, has been isolated recently from children with respiratory tract infections, including upper respiratory infection, bronchiolitis, and pneumonia. The virus has been also detected in immunocompromised adults with respiratory tract infections. A total of 118 nasopharyngeal swab samples from 118 hospitalized young children aged less than 2 years with bronchiolitis who were not infected with human respiratory syncytial virus, influenza A or B, or human metaneumovirus were selected. Three (2.5%) of the 118 samples were positive for HCoV-NL63 by reverse transcription-polymerase chain reaction tests. HCoV-NL63 may be one of the causative agents of bronchiolitis in young children. (C) 2005 Wiley-Liss, Inc.

引用

页码：463 / 465

页数：3

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