Novel syntheses of optically active CC-1065, U-73,975 (adozelesin), U-80,244 (carzelesin), U-77,779 (bizelesin), KW-2189, and DU-86

被引：10

作者：

Fukuda, Y ^{[1
]}

Furuta, H

Shiga, F

Asahina, Y

Terashima, S

机构：

[1] Kyorin Pharmaceut Co Ltd, Cent Res Labs, Nogi, Tochigi 32901, Japan

[2] Sagami Chem Res Ctr, Sagamihara, Kanagawa 229, Japan

来源：

HETEROCYCLES | 1997年 / 45卷 / 12期

关键词：

D O I：

10.3987/COM-97-7920

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title syntheses were achieved by the method featuring oxidative cyclization of the enamino esters [(S)-13 and (S)-24] derived from the 5-aminoindoline [(S)-12], acylation with various structural types of indole-2-carboxylic acids, and formation of cyclopropapyrroloindole moieties.

引用

页码：2303 / 2308

页数：6

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