Depression and Parkinson's disease: a conceptual challenge

Aim: To explore the relation between Parkinson's disease (PD) and depression from a conceptual point of view. Methods: Discussion of the relevant literature on the conceptual, phenomenological and therapeutical aspects of depression in Parkinson's disease. Results: Both semantic confusion and an erroneous belief in the mind-body distinction have contributed to some common misunderstandings of the nosology and etiology of depression in Parkinson's disease. Conclusion: The consequences of a different integrated, neuropsychiatric approach for both diagnosis and treatment are discussed.